Kepsutlu Burcu
Helmholtz-Zentrum Berlin, Germany
Biography
Kepsutlu Burcu is a PhD student and has her expertise in “Evaluation of morphological and functional effects of biologically relevant nanoparticles on cells via X-ray tomography”. With this technique, she showed that nanoparticles induce a significant remodeling of cellular organelle composition within non-apoptotic cells. She also utilized this relatively beneficial technique to track nanoparticle distribution within individual organelles and define the endocytosis pathway of nanoparticles. She found out that nanoparticles are localized in lipid droplets which may be the reason for nanoparticle localization within liver. She also found out that multivesicular bodies may exist without a limiting membrane. All these findings provide invaluable knowledge in the drug delivery field and can be utilized for investigation of different types of drugs with cells.